Posted by on January 24, 2018 10:00 pm
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Categories: Crispr

CRISPR stores a Movie into the DNA of Bacteria | QPT

For the first time, a primitive movie has been encoded in – and then played back from – DNA in living cells.

The research team shows in foundational proof-of-principle experiments that the CRISPR system is able to encode information as complex as a digitized image of a human hand, reminiscent of some of the first paintings drawn on cave walls by early humans, and a sequence of one of the first motion pictures made ever, that of a galloping horse, in living cells.

When a virus infects a bacterium, CRISPR cuts out part of the foreign DNA and stores it in the bacteria’s own genome. The bacterium then uses the stored DNA to recognize the virus and defend against future attacks.

The researchers translated five frames from the race horse in motion photo sequence into DNA. Over the course of five days, they sequentially treated bacteria with a frame of translated DNA. Afterwards, they were able to reconstruct the movie with 90 percent accuracy by sequencing the bacterial DNA.

Although this technology could be used in a variety of ways, the researchers ultimately hope to use it to study the brain.

Scientists say it is a major step toward a “molecular recorder” that may someday make it possible to get read-outs, for example, of the changing internal states of neurons as they develop.

News Sources:

https://wyss.harvard.edu/taking-cells-out-to-the-movies-with-new-crispr-technology/
https://www.eurekalert.org/pub_releases/2017-07/niom-srm071217.php
https://www.nature.com/nature/journal/vaop/ncurrent/full/nature23017.html

Video Sources:
Harvard University
National Institute of Mental Health (NIMH)

Find below some other CRISPR Related News Videos:
CRISPR Gene-Editing tested in a Person for the First time to cure Cancer in China https://www.youtube.com/watch?v=oSiej_HeMdM
Using Light to control CRISPR Genome Editing https://www.youtube.com/watch?v=hG1WYp5W9d4
MIT Engineers program Human Cells to store complex Histories in their DNA https://www.youtube.com/watch?v=hD2cFQmEmNI
CRISPR: Gene Editing Will Change Everything Forever. Is this Genetic Engineering growth Good or Bad? https://www.youtube.com/watch?v=sp9eCYHcP5I
Curing disease by repairing faulty Genes. MIT boosts efficiency of CRISPR genome-editing system. https://www.youtube.com/watch?v=bdnaaJchMnI
Gene Editing Tool “CRISPR Cas9” paves way for Sickle Cell Cure https://www.youtube.com/watch?v=saJ4Be8YiZU
Global CRISPR/Cas9 Market will Cross US$ 1.5 Billion by 2022 https://www.youtube.com/watch?v=_4f6O7AETQw
New gene-editing technology partially restores vision in blind animals https://www.youtube.com/watch?v=SssBxk37_aU
Scientists discover ‘off-switches’ for CRISPR/Cas9 gene editing https://www.youtube.com/watch?v=uSUFm9eZL5Q
Scientists unveil CRISPR-based Diagnostic platform “SHERLOCK” https://www.youtube.com/watch?v=x0fRqCQv8Lg
Using CRISPR to reverse retinitis pigmentosa and restore visual function https://www.youtube.com/watch?v=lZxRMHk3ZbU

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