C2C2: A single-effector CRISPR protein
C2C2: A single-effector CRISPR protein
Broad Institute researchers Omar Abudayyeh and Jonathan Gootenberg describe a new CRISPR system that targets RNA, rather than DNA. The new approach has the potential to open a powerful avenue in cellular manipulation. Whereas DNA editing makes permanent changes to the genome of a cell, the CRISPR-based RNA-targeting approach may allow researchers to make temporary changes that can be adjusted up or down, and with greater specificity and functionality than existing methods for RNA interference.
Copyright Broad Institute, 2016. All rights reserved.
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