Cas9 sheds CRISPR light on RNA/ Cell, March 17, 2016 (Vol. 165, Issue 2)
Still focusing on genome editing using CRISPR? How about reprogram Cas9 to target RNA? For the first time, Gene Yeo @ UCSD and Jennifer Doudna @UC Berkley and colleagues develop a Cas9-based system to track endogenous RNA in living cells. Check out the Cell paper here: http://www.cell.com/cell/fulltext/S0092-8674(16)30204-5 and brainstorm other cool applications this technology can bring us in the future!
David A. Nelles, Mark Y. Fang, Mitchell R. O’Connell, Jia L. Xu, Sebastian J. Markmiller, Jennifer A. Doudna, and Gene W. Yeo (2014). Programmable RNA Tracking in Live Cells with CRISPR/Cas9. Cell 165.
And read more great research at http://www.cell.com/cell/home.