CRISPR: History of Discovery
The development of this video was funded under NIE Incentivsing ICT Use Innovation Grant (I3G 02/16 CZ).
What does it take to invent the next iPhone? Or find the next penicillin? Does it take a genius like Steve Jobs or Alexander Fleming, who in their garage or isolated laboratory, had an eureka moment and magically discovered the next big thing? What is the formula to discover the next breakthrough?
It all begins with observation. In 1987, when a group of Japanese scientists discovered an odd DNA sequence in a type of bacteria, the E.coli. These repeated sequences were something that had never been seen before. They are palindromic, meaning they read identically forward and backward, for about 30 bases, and are separated by spacers of roughly about 36 bases that are not palindromic in nature.
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