Posted by on January 26, 2018 1:30 pm
Tags:
Categories: Crispr

Broad Wins CRISPR Patent Interference Case

Broad Wins CRISPR Patent Interference Case:techniques, patent, intellectual property, Cas.

biotechnology:https://youtu.be/cT6nmVok5Wc

Broad Wins CRISPR Patent Interference Case

The USPTO’s Patent Trial and Appeal Board has ruled in favor of the Broad Institute of MIT and Harvard retaining intellectual property rights covered by its patents for CRISPR gene-editing technology.

The University of California, Berkeley, has filed an appeal with the US Court of Appeals for the Federal Circuit in Washington, DC, challenging the February ruling of the US Patent and Trademark Office’s Patent Trial and Appeal Board (PTAB), which determined that the patent issued in 2014 for Feng Zhang and colleagues’ work on CRISPR gene-editing technology at the Broad Institute of MIT and Harvard does not directly compete with a patent filed previously by the UC Berkeley team. In other words, the PTAB ruled that the two parties’ claims were separately patentable.
“Ultimately, we expect to establish definitively that the team led by Jennifer Doudna and Emmanuelle Charpentier was the first to engineer CRISPR-Cas9 for use in all types of environments, including in non-cellular settings and within plant, animal and even human cells,” molecular and cell biologist Edward Penhoet, associate dean of biology at UC Berkeley and a special adviser on CRISPR to the UC president and UC Berkeley chancellor, said in a statement.
But in a statement from the Broad, Chief Communications Officer Lee McGuire expressed confidence in the institute’s existing CRISPR patent. “Given that the facts have not changed, we expect the outcome will once again be the same,” he said. “To overturn the PTAB decision, the Court would need to decide that the PTAB committed an error of law or lacked substantial evidence to reach its decision. Given the careful and extensive factual findings in the PTAB’s decision, this seems unlikely.”
US Patent and Trademark Office’s Patent Trial and Appeal Board (PTAB) today (February 15) issued a ruling on a patent dispute regarding CRISPR gene editing. The judges declared that the work by Jennifer Doudna of the University of California, Berkeley, and colleagues (including Emmanuelle Charpentier, then at the University of Vienna) does not directly compete with the work of Feng Zhang at the Broad Institute of MIT and Harvard, which was granted the original CRISPR patent in April 2014.
“Broad has persuaded us that the parties claim patentably distinct subject matter,” the court wrote in its 51-page decision (which accompanied its two-page order). “Broad provided sufficient evidence to show that its claims, which are all limited to CRISPR-Cas9 systems in a eukaryotic environment, are not drawn to the same invention as UC’s claims, which are all directed to CRISPR-Cas9 systems not restricted to any environment.”
“It looks like Broad has the decisive victory in this case,” Jake Sherkow of New York Law School told The Scientist.
UC Berkeley said that, while it “respects” today’s ruling and is “pleased” that its patent application can now move forward, the university is considering “all options for possible next steps in this legal process, including the possibility of an appeal of the PTAB’s decision,” a statement read. “We continue to maintain that the evidence overwhelmingly supports our position that the Doudna/Charpentier team was the first group to invent this technology for use in all settings and all cell types.”
If UC Berkeley does appeal to the US Court of Appeals for the Federal Circuit, “those cases take roughly a year from soup to nuts,” said Sherkow. In that circumstance, a decision would likely come from the appellate court “sometime in February or March of next year.”
The patent battle between the institutions over CRISPR technology started in January 2016, when the PTAB granted UC Berkeley’s request for a patent interference between its filed application for the use of CRISPR technology in vitro and in prokaryotes and Zhang’s patent that specifically described the use of CRISPR in eukaryotes. In December, the court heard the only oral arguments to be given on the case. UC Berkeley’s lawyer argued that Zhang’s accomplishments in eukaryotes were an obvious extrapolation of Doudna and Charpentier’s work, and the Broad’s patent thus interfered with the earlier application; the Broad’s lawyer argued that it wasn’t obvious, and Zhang’s work deserved the patent that it was granted.

According to the scientist.

Thank you for watching!

Don’t forget to like this video, and subscribe for the next video.

#researchsciences #sciencesdiscovery

Leave a Reply