A serious new hurdle for CRISPR: Edited cells might cause cancer, two studies find
Source: A serious new hurdle for CRISPR: Edited cells might cause cancer, two studies find
E
diting cells’ genomes with CRISPR-Cas9 might increase the risk that the altered cells, intended to treat disease, will trigger cancer, two studies published on Monday warn — a potential game-changer for the companies developing CRISPR-based therapies.
In the studies, published in Nature Medicine, scientists found that cells whose genomes are successfully edited by CRISPR-Cas9 have the potential to seed tumors inside a patient. That could make some CRISPR’d cells ticking time bombs, according to researchers from Sweden’s Karolinska Institute and, separately, Novartis.
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Published at Wed, 13 Jun 2018 01:09:28 +0000
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